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They may mean liver problems or they may not. However, it must be emphasized that higher-than-normal levels of these liver enzymes should not be automatically equated with liver disease. What do high (elevated) liver tests (AST and ALT) mean?ĪST (SGOT) and ALT (SGPT) are reasonably sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests.
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The focus of this article is mainly on the most common liver enzymes, AST and ALT. In addition to AST and ALT, alkaline phosphatase, 5' nucleotidase, and gamma-glutamyl transpeptidase (GGT) are a few of the other enzymes located in the liver. Other blood tests pertaining to the liver are measurements of some of the other enzymes found the liver. If the liver is injured or damaged, the liver cells spill these enzymes into the blood, raising the AST and ALT enzyme blood levels and signaling liver disease. These enzymes are normally predominantly contained within liver cells and to a lesser degree in the muscle cells. They include aspartate aminotransferase (AST or SGOT) and alanine aminotransferase (ALT or SGPT). Enzymes help to speed up (catalyze) routine and vital chemical reactions in the body.Īmong the most sensitive and widely used liver enzymes are the aminotransferases. Enzymes are proteins that are present throughout the body, each with a unique function. But when the liver is injured for any reason, these enzymes are spilled into the blood stream. Under normal circumstances, these enzymes mostly reside within the cells of the liver. An initial step in detecting liver damage is a simple blood test to determine the level of certain liver enzymes (proteins) in the blood. These tests can be used to assess liver functions or liver injury. Liver blood tests are some of the most commonly performed blood tests. What are common liver blood function tests? Patient Comments: Liver Blood Tests - Why Were You Tested?.Patient Comments: Liver Blood Tests - Experience.Patient Comments: Liver Blood Tests - Diagnosis.Liver Function Tests (Normal, Low, and High Levels & Results) Center.What other liver enzymes cause medical problems?.How do health care professionals monitor a person's liver blood values?.How are healthy people evaluated for mild to moderate rises in AST/ALT levels? (continued).How are healthy people evaluated for mild to moderate rises in AST/ALT levels?.What are some of the less common causes of elevated liver blood tests? (continued).
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